徐洲更的头像

徐洲更

中国科学院分子植物科学卓越创新中心（CEMPS）博士后（王佳伟研究组）

浙江农林大学农学学士学位，中国科学院大学博士学位。主要研究方向为植物单细胞测序与跨物种细胞图谱构建。研究成果发表于 Cell、Science、Molecular Plant 等国内外重要学术期刊，相关成果入选 2024 年度"中国生命科学十大进展"。

入选"中国科学院特别研究助理资助项目"和"国家资助博士后研究人员计划（B档）"，并获得 2025 年度博士后科研业绩评估考核资助（一档）。

具备优秀的学习能力和协作沟通能力，乐于探索并能够主动提出和解决问题。

基本信息

姓名：徐洲更

单位：中国科学院分子植物科学卓越创新中心

公众号：洲更的第二大脑

博客：xuzhougeng.top

教育经历

  • 2012-2016   浙江农林大学 — 农学学士学位
  • 2016-2023   中国科学院分子植物科学卓越创新中心 — 遗传学博士学位

工作经历

  • 2023 年 7 月至今 — 中国科学院分子植物科学卓越创新中心，博士后

专业技能

  • 基因组学的相关分析
  • 熟悉 Linux 和 Shell 编程，具备服务器管理能力
  • 熟悉 R 和 Python 编程语言，并了解数据结构和算法的应用
  • 基础的网站开发能力
  • 运用 AIGC 辅助项目开发

其他经历

自 2016 年读研以来，持续在网络上发表生物信息学相关教程，全网阅读量超过 200 万。在哔哩哔哩录制的生物信息学教学视频累计播放量约 10 万次，并通过邮件等方式帮助初学者答疑解惑。

发表论文

2025

  1. Xin Ming, Mu-Chun Wan, Zheng-Da Zhang, Hao-Chen Xue, Ya-Qi Wu, Zhou-Geng Xu, Heng Lian, Meng-Ting Yuan, Yan-Xia Mai, Ying-Xiong Hu, Ke Liu, Jian Gao, Qiao-Lin Shao, D. Blaine Marchant, Brad Nelms, Virginia Walbot & Jia-Wei Wang. FX-Cell: a method for single-cell RNA sequencing on difficult-to-digest and cryopreserved plant samples. Nature Methods, 2025. https://doi.org/10.1038/s41592-025-02900-2
  2. Shipeng Guo, Yanshuang Jiang, Jieya Zou, Mei Lu, Daxue Li, Qian Zhang, Weiwei Li, Lina Mao, Shengchun Liu, Zhougeng Xu, et al. GPSAdb 2.0: an expanded atlas of gene-perturbation transcriptomes with enhanced tools for regulatory gene discovery. Nucleic Acids Research, 2025. https://doi.org/10.1093/nar/gkaf1077
  3. Xiaofan Lu, Kailai Li, Zongcheng Li, Anqi Lin, Long Zhao, Rongfang Shen, Zhougeng Xu, Jianing Gao, et al. FigureYa: A Standardized Visualization Framework for Enhancing Biomedical Data Interpretation and Research Efficiency. iMetaMed. https://doi.org/10.1002/imm3.70005
  4. Hao-Chen Xue, Zhou-Geng Xu, Yu-Jie Liu, et al. A Unified Cell Atlas of Vascular Plants Reveals Cell-Type Foundational Genes and Accelerates Gene Discovery. Cell, 2025. https://doi.org/10.1016/j.cell.2025.07.036

2024

  1. Dong Zhai, Lu-Yi Zhang, Ling-Zi Li, Zhou-Geng Xu, et al. Reciprocal Conversion between Annual and Polycarpic Perennial Flowering Behavior in the Brassicaceae. Cell, 2024. https://doi.org/10.1016/j.cell.2024.04.047
  2. Chuan-Miao Zhou, Jian-Xu Li, Tian-Qi Zhang, Zhou-Geng Xu, et al. The Structure of B-ARR Reveals the Molecular Basis of Transcriptional Activation by Cytokinin. PNAS, 2024. https://doi.org/10.1073/pnas.2319335121
  3. Haibao Tang, Vivek Krishnakumar, Xiaofei Zeng, Zhougeng Xu, et al. JCVI: A Versatile Toolkit for Comparative Genomics Analysis. iMeta. https://doi.org/10.1002/imt2.211

2023

  1. L. Wang, M.-C. Wan, R.-Y. Liao, J. Xu, Z.-G. Xu, et al. The maturation and aging trajectory of Marchantia polymorpha at single-cell resolution. Developmental Cell, 2023.
  2. Hong-Bo Tang, Juan Wang, Long Wang, Guan-Dong Shang, Zhou-Geng Xu, et al. Anisotropic cell growth at the leaf base promotes age-related changes in leaf shape in Arabidopsis thaliana. The Plant Cell, 2023. https://doi.org/10.1093/plcell/koad031
  3. Ling-Zi Li, Zhou-Geng Xu, Tian-Guang Chang, et al. Common evolutionary trajectory of short life-cycle in Brassicaceae ruderal weeds. Nature Communications 14, 290 (2023). https://doi.org/10.1038/s41467-023-35966-7

2022

  1. Shipeng Guo, Zhougeng Xu, Xiangjun Dong, et al. GPSAdb: a comprehensive web resource for interactive exploration of genetic perturbation RNA-seq datasets. Nucleic Acids Research, 2022. https://doi.org/10.1093/nar/gkac1066
  2. Chen-Yi Li, Lei Yang, Yan Liu, Zhou-Geng Xu, et al. The Sage Genome Provides Insight into the Evolutionary Dynamics of Diterpene Biosynthesis Gene Cluster in Plants. Cell Reports, 2022. https://doi.org/10.1016/j.celrep.2022.111236
  3. Guan-Dong Shang, Zhou-Geng Xu, M.-C. Wan, et al. FindIT2: an R/Bioconductor package to identify influential transcription factor and targets based on multi-omics data. BMC Genomics 23, 272 (2022). https://doi.org/10.1186/s12864-022-08506-8
  4. Jian Gao, Ke Zhang, Ying-Juan Cheng, Sha Yu, Guan-Dong Shang, Fu-Xiang Wang, Lian-Yu Wu, Zhou-Geng Xu, et al. A Robust Mechanism for Resetting Juvenility during Each Generation in Arabidopsis. Nature Plants 8(3):257–268 (2022). https://doi.org/10.1038/s41477-022-01110-4
  5. L.-Y. Wu, G.-D. Shang, F.-X. Wang, J. Gao, M.-C. Wan, Z.-G. Xu, and J.-W. Wang. Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration. Developmental Cell, 2022.

2021

  1. Kun Huang, Xue-Xue Wu, Chen-Lu Fang, Z.-G. Xu, et al. Pol IV and RDR2: A two-RNA-polymerase machine that produces double-stranded RNA. Science, 2021. https://www.science.org/doi/10.1126/science.abj9184
  2. Yu-Jin Cheng, Guan-Dong Shang, Z.-G. Xu, et al. Cell division in the shoot apical meristem is a trigger for miR156 decline and vegetative phase transition in Arabidopsis. PNAS 118 (2021). https://doi.org/10.1073/pnas.2115667118
  3. Fu-Xiang Wang, Guan-Dong Shang, Lian-Yu Wu, Yan-Xia Mai, Jian Gao, Zhou-Geng Xu, Jia-Wei Wang. Protocol for assaying chromatin accessibility using ATAC-seq in plants. STAR Protocols 2(1):100289 (2021). https://doi.org/10.1016/j.xpro.2020.100289

2020

  1. Bin-Bin Ye, Guan-Dong Shang, Yu Pan, Zhou-Geng Xu, et al. AP2/ERF Transcription Factors Integrate Age and Wound Signals for Root Regeneration. The Plant Cell 32(1):226–241 (2020). https://doi.org/10.1105/tpc.19.00378
  2. Fu-Xiang Wang, Guan-Dong Shang, Lian-Yu Wu, Zhou-Geng Xu, et al. Chromatin Accessibility Dynamics and a Hierarchical Transcriptional Regulatory Network Structure for Plant Somatic Embryogenesis. Developmental Cell 54(6):742–757.e8 (2020). https://doi.org/10.1016/j.devcel.2020.07.003

2019

  1. Tian-Qi Zhang, Zhou-Geng Xu, Guan-Dong Shang, Jia-Wei Wang. A Single-Cell RNA Sequencing Profiles the Developmental Landscape of Arabidopsis Root. Molecular Plant 12(5):648–660 (2019). https://doi.org/10.1016/j.molp.2019.04.004